Dimethyl sulfoxide (DMSO)yog cov kuab tshuaj siv dav uas yog miscible nrog dej thiab feem ntau cov kuab tshuaj organic. Nws yog thawj zaug tsim nyob rau hauv 1866 los ntawm Chile chemist Alexander Saytzeff, thiab loj - teev ntau lawm tsim nyob rau hauv lub xyoo pua 20th los ntawm dimethyl sulfide zoo tu qab tso nyob rau hauv ntoo pulping.
Cov khoom tseem ceeb ntawm dMSO
| Qhov tshwm sim | Ntshiab, xim tsis muaj kua |
| Boiling Point | 189 degree |
| Melting Point | 18.5°C dej |
| Qhov ntom | 1.10 g / cm³ |
| Solubility | Miscible nrog dej & organics |
| Polarity | Polar aprotic hnyav heev |
| Flash Point | ~ 89 degree |
DMSO Solvent Siv li cas hauv Tshuaj Synthesis?
DMSO yog qhov nruab nrab cov tshuaj tiv thaiv hauv cov organic chemistry vim tias nws dissolves ntau yam ntawm cov reactants, suav nrog ntau cov organic tsis zoo soluble, uas txhim kho reactant sib cuag thiab hloov dua siab tshiab. Nws lub luag haujlwm tseem ceeb tau sau tseg hauv qab no.
| Hom tshuaj tiv thaiv | Lub luag haujlwm ntawm DMSO | Piv txwv |
|---|---|---|
| SN2 hloov | Polar aprotic hnyav; tawm nucleophiles ntau reactive | Cyanide los yog azide hloov chaw ntawm alkyl halides |
| Nucleophilic aromatic hloov pauv (SNAR) | Stabilizes nqi intermediates; tso cai rau qhov kub thiab txias | Halex fluorination ntawm aryl chlorides |
| Kev tshem tawm thiab lub hauv paus- cov tshuaj tiv thaiv nruab nrab | Txhim khu lub hauv paus zog | Dehydrohalogenation |
| Oxidation | Oxidant (nrog rau activator) | Swern, Parikh-Doering thiab Kornblum oxidation |
| Ylide chemistry | Cov kuab tshuaj thiab, nrog cov hauv paus muaj zog, ua ntej ntawm dimsyl anion | Corey-Chaykovsky epoxidation |
| Hlau -catalyzed coupling | Siab -boiling polar medium | Heck thiab cuam tshuam txog -kev sib txuas lus |
- Nucleophilic hloov pauv, tshem tawm thiab lub hauv paus- cov tshuaj tiv thaiv catalyzed: raws li cov polar aprotic hnyav, DMSO solvates cations zoo tab sis tawm cov anions tsawg dua, uas ua rau cov nucleophilicity thiab feem ntau ua rau cov tshuaj tiv thaiv SN2.
- Oxidation: DMSO nws tus kheej ua cov oxidant, nrog rau cov activator (oxalyl chloride hauv Swern, SO₃·pyridine hauv Parikh-Doering), hloov cov cawv rau aldehydes lossis ketones hauv cov mob me.
- Advanced cov ntaub ntawv: hluavtaws polymers, conductive cov ntaub ntawv thiab tshwj xeeb resins.
- Electrochemistry thiab catalysis: kev tshawb fawb roj teeb thiab cov tshuaj tiv thaiv electrochemical, qhov twg DMSO txhawb nqa ion thauj thiab cov tshuaj tiv thaiv.
- Siab- qhov kub thiab txias: qhov kub ntawm qhov kub ntawm txog 189℃tso cai rau cov tshuaj tiv thaiv kub thiab cov kuab tshuaj poob qis, uas txhawb nqa loj- teev ntau lawm.
DMSO vs Lwm Polar Aprotic Solvents
| Solvent | Boiling point | Melting point | Dielectric qhov tsis tu ncua (kwv yees) |
|---|---|---|---|
| DMSO | 189 degree | 18.5°C dej | 47 |
| DMF | 153 degree | -61 degree | 37 |
| DMAc | 165 degree | -20 degree | 38 |
| NMP | 202 degree | -24 degree | 32 |
| Cov tshuaj acetonitrile | 82 degree | -45 degree | 37 |
DMSO muaj lub siab tshaj plaws polarity ntawm pab pawg thiab dissolves ob ntsev thiab organics, tab sis nws kuj siab melting point txhais tau tias nws muaj peev xwm solidify nyob rau hauv txias cia. Rau qhov sib piv hnyav, saibsolubility ntawm dimethylacetamide (DMAc).
Dimethyl sulfoxide DMSO Solvent Organic Chemistry
Cov ntaub ntawv kev nyab xeeb
Los xyuas kom meej qhov zoo thiab kev nyab xeeb ntawm DMSO tshuaj:
- Khaws rau hauv qhov chaw txias, qhuav, zoo - qhov cua.
- Khaws kom deb ntawm cov muaj zog oxidizers.
- Siv cov thawv airtight los tiv thaiv kom tsis txhob ya raws.
- Tsis txhob sib cuag ntawm daim tawv nqaij (cov tshuaj tuaj yeem nqus tau los ntawm daim tawv nqaij).
txog peb
Tianjin Gnee Biotech Co., Ltd. (GNEE BIO), tsim nyob rau hauv 2021, yog ib tug kws tshuaj thiab exporter pab distributors, manufacturers thiab cov neeg siv khoom thoob ntiaj teb. Peb ua haujlwm nrog cov neeg tsim khoom tsim nyog thiab siv kev tswj xyuas nruj zoo thoob plaws hauv cov txheej txheem muab khoom. Cov ntawv pov thawj suav nrog REACH, ISO, FMQS thiab HALAL muaj nyob rau ntawm kev thov.
Vim li cas Yuav los ntawm GNEE BIO?
- Cov ntaub ntawv nrog txhua qhov kev txiav txim: COA, TDS thiab SDS / MSDS. SGS thib peb- tog neeg soj ntsuam muaj nyob rau ntawm kev thov.
- Ntim thiab xa khoom yooj yim: steel nruas, IBC tso tsheb hlau luam thiab ISO tso tsheb hlau luam; FOB, CFR thiab CIF cov lus hais; warehouses hauv Qingdao, Tianjin thiab Shanghai.
- Export kev: xa khoom mus rau Tebchaws Europe, North America, South America, Middle East, Asia Pacific thiab Africa.
- Teb ceev ceev: nug cov lus teb hauv 24 teev.
Thov ib daim ntawv tsocai, COA lossis SDS- los yog emailsales@gneebio.com
GNEE BIO Khoom ntim khoom
| Ntim Hom | Net nyhav |
|---|---|
| Hlau Nruas | 250 kg |
| IBC Tank | 12 50kg |
| ISO Tank | Kev xa khoom ntau |
Neeg tuaj xyuas
