Gentamicin Sulfate yog dab tsi?
Gentamicin Sulfate Injection yog ib qho tshuaj siv los kho cov kab mob loj heev, xws li endocarditis, mob ntsws, mastitis, thiab kab mob urinary. Cov tshuaj tua kab mob no tuaj yeem siv los tiv thaiv kev loj hlob ntawm cov kab mob tshuaj tiv thaiv kab mob. Gentamicin sulfate kuj tau sau tseg ua prophylaxis rau kev phais.
Raws li cov tshuaj tua kab mob aminoglycoside, nws siv nws cov tshuaj tua kab mob los ntawm kev tsom mus rau cov kab mob ribosomes, tshwj xeeb tshaj yog 30S subunit, yog li cuam tshuam nrog protein synthesis. Nws qhia txog kev ua haujlwm tawm tsam gram-positive thiab gram-negative kab mob. Qhov kev cuam tshuam no hauv kev tsim cov protein ua rau inhibition ntawm cov kab mob loj hlob thiab rov ua dua tshiab.
Dab tsi yog gentamicin sulfate siv rau hauv cov tsiaj?
- Nyuj:Gentamicin Sulfate Injection feem ntau yog siv rau hauv nyuj rau kev kho mob ntawm cov kab mob, xws li mob ntsws, septicemia, thiab kab mob los ntawm E. coli. Kev siv feem ntau yog tshwj tseg rau cov xwm txheej uas lwm cov tshuaj tua kab mob ua tsis tau lossis tsis ua haujlwm vim yog cov qauv tiv thaiv.
- Npua:Hauv npua, nws yog siv nyob rau hauv cov tub ntxhais hluas piglets los tiv thaiv cov kab mob xws li kab mob enteritis thiab mob ntsws los ntawm cov kab mob uas raug rau gentamicin.
- Cov dev:Rau cov dev, Gentamicin Sulfate feem ntau yog siv los kho cov kab mob uas cuam tshuam rau ntawm daim tawv nqaij, pob ntseg, thiab urinary ib ntsuj av. Cov tshuaj yuav siv tau nrog rau lwm yam kev kho mob, xws li tshuaj pleev ib ce lossis tshuaj tua kab mob hauv qhov ncauj, nyob ntawm qhov chaw thiab qhov hnyav ntawm tus kab mob.
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Nees:Gentamicin Sulfate Injection yog siv rau kev kho mob ntawm cov kab mob ua pa, kab mob hauv lub qhov txhab, thiab kab mob plab los ntawm kab mob gram-tsis zoo. Nws feem ntau yog ib feem ntawm kev kho ua ke, tshwj xeeb tshaj yog nyob rau hauv cov xwm txheej tseem ceeb uas xav tau kev pab them nqi dav dav.
Kev ceev faj ntawm gentamicin sulfate
(1) Gentamycin tuaj yeem siv ua ke nrog -lactam tshuaj tua kab mob los kho cov kab mob hnyav, tab sis nws tsis sib xws thaum sib xyaw hauv vitro.
(2) Ua ke nrog penicillin, cov khoom no muaj cov nyhuv synergistic ntawm streptococci.
(3) Nws muaj kev nyuaj siab ua pa thiab yuav tsum tsis txhob txhaj tshuaj intravenously.
(4) antagonism tuaj yeem tshwm sim ua ke nrog tetracycline thiab erythromycin.
(5) Kev sib xyaw nrog cephalosporins tuaj yeem txhim kho nephrotoxicity.
