Ivermectin yog ib qho tshiab, dav-spectrum, muaj txiaj ntsig zoo, thiab muaj cov tshuaj tua kab mob tsis muaj tshuaj tiv thaiv kab mob. Nws muaj txiaj ntsig tshwj xeeb hauv kev tshem tawm cov kab mob sab hauv thiab sab nraud, tshwj xeeb tshaj yog nematodes thiab arthropods. Txawm li cas los xij, nws tsis muaj txiaj ntsig tiv thaiv kab mob qog, kab mob, thiab protozoa.
Cov kab mob sab hauv uas tuaj yeem kho nrog ivermectin muaj xws li kab mob plab hnyuv (feem ntau roundworms) hauv nees, nyuj, npua, yaj, thiab tshis nrog rau cov kab mob ntsws hauv nyuj thiab npua. Cov kab mob sab nraud uas tuaj yeem kho nrog ivermectin hauv cov tsiaj loj muaj xws li nab, mites, thiab grubs.
Raws li ib tug macrocyclic lactone antiparasitic tshuaj, ivermectin lub mechanism ntawm kev txiav txim tawm tsam nematodes thiab arthropods koom nrog nce kev tso tawm ntawm inhibitory neurotransmitter -aminobutyric acid (GABA) thiab qhib glutamate-gated chloride ion channels. Qhov no txhim kho cov permeability ntawm neural daim nyias nyias mus rau chloride ions, yog li cuam tshuam kev sib kis ntawm neural signals. Thaum kawg, qhov no ua rau tuag tes tuag taw ntawm cov kab mob hauv lub paj hlwb, ua rau lawv cov leeg nqaij tsis muaj peev xwm cog lus, uas ua rau cov kab mob tuag taus.